Re: Mike Behe: Response to critics concerning peer-review

From: Stephen E. Jones (sejones@iinet.net.au)
Date: Sat Aug 05 2000 - 09:16:36 EDT

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    Reflectorites

    To answer the charge that the ID movement never publishes articles in
    peer reviewed scientific journals and therefore is not science, here is
    previously private correspondence between Mike Behe and editors of
    scientific journals (names deleted), which have now been posted to the
    Discovery Institute website.

    These shows that the real problem is not the non-submission of journals by
    ID theorist, but the refusal of scientific journals to publish ID articles.

    Steve

    ====================================================
    http://www.discovery.org/embeddedRecentArticles.php3?id=450

    Correspondence with Science Journals:
    Response to critics concerning peer-review

    Michael J. Behe
    Discovery Institute
    August 2, 2000
    -------------------------------------------------------------------------------
    I. Introduction

    Much of the material shown posted as "responses to critics" on this website
    was originally submitted to several science journals for consideration for
    publication. In every case it was turned down. Below I have included the
    correspondence between the journals and myself. Names of journals and
    individuals have been omitted. The take-home lesson I have learned is that,
    while some science journal editors are individually tolerant and will
    entertain thoughts of publishing challenges to current views, when a group
    (such as the editorial board) gets together, orthodoxy prevails. Admittedly
    the conclusion is based on a small number of experiences, yet years go by
    while the experiences accumulate. So far my experience with philosophy
    journals has been quite different, and I have published a reply to specific
    criticisms in Philosophy of Science. (Behe, Michael J. (2000). Self-
    organization and irreducibly complex systems: A reply to Shanks and
    Joplin. Philosophy of Science 67, 155-162.)

    II. A brief response

    I initially emailed the editor of a journal in the field of evolution about the
    possibility of publishing a full-length reply-to-critics paper. As seen below,
    he suggested a very much-shortened paper. The shortened version
    essentially consisted of section II from the article "In Defense of the
    Irreducibility of the Blood Clotting Cascade" on this website. I argued that
    Darwinian scenarios need to include more than just a general invocation of
    gene duplication to be justified. The correspondence includes: (1) an email
    from the editor to me; (2) my letter back to him; 3) his letter rejecting the
    manuscript; (4) the criticisms of the reviewer; (5) a response letter from
    me.

    [The following is an email from the editor of the journal.]

    Subject: Re: inquiry about submission
    Date: Mon, 7 Jun 1999 10:21:54 ?0500
    From: [the editor]
    To: "Michael J. Behe"

    Hi Mike,

    I'm torn by your request to submit a (thoughtful) response to critics of your
    non-evolutionary theory for the origin of complexity. On the one hand I am
    painfully aware of the close-mindedness of the scientific community to non-
    orthodoxy, and I think it is counterproductive. But on the other hand we
    have fixed page limits for each month's issue, and there are many more
    good submissions than we can accept. So, your unorthodox theory would
    have to displace something that would be extending the current paradigm.

    What I would suggest you do is to write something quite short--a letter--
    that would fit in, say, three pages or so of [the journal]. Then, if your letter
    is sufficiently provocative and lively, I might have an easier time convincing
    the other editors of its worth.

    [The following is my next response to the editor.]

    June 11, 1999

    Dear Professor...,

    Here is the short response to critics that I discussed with you earlier, which
    I would like to be considered for publication as a letter in the [journal]. I
    hope you find it to be fruitfully provocative. The text is a little less than
    3,000 words, which I calculate should fit in about three pages, as you
    suggested. Since it is a short letter, I didn't include an abstract; if one is
    needed, the first paragraph could serve. I have listed the names of a few
    potential reviewers on an attached page. Best wishes.

    Sincerely,

    Michael J. Behe
    Professor of Biological Sciences

    [The following the editor's response to my letter]

    July 12, 1999

    Dear Dr. Behe,

    Because of the controversial nature of your letter to [this journal], and
    concern about whether it would be appropriate for a scientific journal, I
    asked a senior [journal] advisor to take a look at your submission. As you
    will see, the accompanying review identifies many apparent flaws in your
    arguments, and also questions the basic premise of your arguments, that
    complex systems cannot be dissected to reveal individual components'
    roles. I concur with this reviewer's sentiment: complex systems are being
    unraveled!

    So, I am going to take the liberty as Editor not to seek additional reviews,
    and deny the request to have your letter published in [this journal]. I would
    like to encourage you to seek new evidence for your views, but of course,
    that evidence would likely fall outside of the scientific paradigm, or would
    basically be denials of conventional explanations. You are in for some
    tough sledding.

    Sincerely,

    [The editor]

    [The comments of the senior advisor follow]

    Review of "Obstacles to gene duplication as an explanation for complex
    biochemical systems" by Michael Behe.

    In the section "Meaning of explanation," the author harps on the extreme
    difficulty of elucidating complicated cellular interaction systems and of
    tracing the evolution of biological complexity. It is ironic that he should
    voice his concerns just as technical as well as conceptual progress has
    opened the door to investigating on a much larger scale than heretofore the
    mechanisms of development, and the increase in gene interaction
    complexity along certain lines of descent. Michael Behe is depicting a
    hopeless situation for the biological sciences, or at least for their
    evolutionary aspects, just as biology is proceeding through a glorious age.

    A classical error of people who believe that complex gene interaction
    systems and other complex biological systems present an insuperable
    difficulty to evolutionary science is to imply that every component of the
    system has or has had only one function. In reality, every gene, or its
    ancestors, or its duplicated brothers and cousins, or all of these, usually
    exert multiple functions and can be re-mobilized for building up new
    complex systems or can be dropped from a complex system without being
    dropped from the functioning genome. The function of the system itself
    may change (an oft quoted morphological example: folds that act as gliders
    related to wings); intermediate stages function differently from the terminal
    stage considered, but do function, indeed. If evolutionary pathways were
    difficult to find, nature faced these difficulties and solved them. The
    scientist's job is just to follow nature, and that he believes he can do.

    It is interesting to show--Behe examines this claim--that by knocking two
    genes out of this cascade, the resulting organisms are less abnormal than
    those that have lost only one of two genes. Yet, it is by no means necessary
    to be able to provide such a demonstration. Not being able to provide it
    does not authorize anyone to consider the system as "irreducibly" complex,
    in Behe's metaphysical sense of irreducible.

    On the other hand, the mutational acquisition of modified or new functions
    by duplicated genes has been witnessed many times by sequence
    comparisons and other approaches, and there is no trace of an "irreducible"
    difficulty here either, despite Behe's claims.

    This reviewer is no authority on the blood clotting cascade, but if a
    plausible model for its evolutionary development, compatible with all
    known facts, has indeed not been generated so far, the remaining question
    marks are not threat to science--on the contrary, they are a challenge added
    to thousands of other challenges that science met and meets. In this
    instance, too, science will be successful.

    Is that too bold a prediction? On the contrary, it is not bold. If science, in
    the modern sense of the word (defined by its method), were only just
    beginning its career, onlookers would naturally be divided into optimists
    and pessimists. But, as young as science still is, its accomplishments have
    verified over and over again that the world of the observable and the
    measurable is understandable in terms of the observed and measured.
    Pessimism in this respect has come to lack intellectual status.

    In the face of this evidence, Dr. Behe's stance is quasi-heroic, but it is
    heroism at the service of a lost and mistaken cause. He is not deterred by
    the fact that molecular biology is only about 50 years old, that during this
    period it has generated an almost overwhelming amount of fundamental
    understanding, that more understanding is obviously on its way; further,
    that the study of the molecular bases of development had to wait for its
    turn: it was able to take off seriously only within the last decade. All of
    these studies will be amplified if there is peace in the world, and many
    biological problems that Dr. Behe today uses as drums to proclaim his faith
    will be solved in ways that cannot be but disappointing to him.

    The trust expressed by the present referee is based on the lessons of several
    hundred years of history of science. It is really a very short history judged
    in terms of human history in general, and, considering the recorded
    accomplishments, it takes a fair amount of intellectual "chuzpah" to
    reproach science for the understanding that it has not yet achieved.

    This reviewer thinks that there is a great deal of misunderstanding around
    the role of intelligence in the world. The world itself, through the
    interactions that take place under the reign of natural law, manifests a sort
    of intelligence--an intelligence much greater than our intelligence--out of
    which our intelligence has very likely arisen as a product. No wonder, then,
    that, to our intelligence, the universe appears intelligent: there is a close
    kinship between the universe and our mind--as one would expect, since our
    intelligence is shaped so as to permit us to get along in the world. ("...So as
    to permit us . . .": language often induces us to seem to express the
    presence of an intent when none is implied; none is here.) Consistently to
    use the phrase "intelligent design" instead of God is almost cheating, since
    this use has an ambiguous relation to the presence in the universe of a sort
    of intelligence that, except perhaps in a pantheistic sense if one wishes to
    think so, has no implication regarding the existence of a God. God, here,
    stands for a being that combines consciousness, will, and universal power.

    Of course science has its limits, but they are surely not where Behe places
    them; they are not, indeed, in the realm of biological evolution. The
    perception of science's limits will evolve as science itself evolves, and the
    limits won't furnish an argument in favor of intelligent design in the sense
    of a design imagines by a universal "person." The argument will be in favor
    of the finiteness of the analytical powers of the human mind. The limits of
    science will probably be recognized as being, in part, imposed by the
    position in the universe of the intelligent (human) observer. Whatever
    God's role in the universe, if any, biology will be understood without
    reference to him. That is implied by the essence of science.

    Behe wants to be able to say that this is not so, and he needs to say it very
    quickly, because every day any conceivable ground for making his
    statement shrinks further. The faith of scientists is that the world of
    phenomena can be understood, and that the transformations of this world
    leading up to the present state of affairs can be understood. Developments
    conform every day that, progressively, scientists are winning this bet.
    Whatever is discovered, the most surprising as well as the less surprising,
    will be part of nature: the supernatural has no place in the observable and
    measurable.

    Metaphysicians who want science to speak out in favor of their beliefs, if
    not demonstrate them, are already put in a tight spot by the science of
    yesterday and have nothing to fear more than the science of tomorrow.

    In this referee's judgment, the manuscript of Michael Behe does not
    contribute anything useful to evolutionary science. The arguments
    presented are weak.

    Incidentally, publication in a scientific journal of this article could not be
    construed as anything resembling a First Amendment right. Naysayers such
    as Michael Behe have not been muzzled. They have repeatedly aired their
    point of view, and so be it.

    If Behe were right in spite of all, it would become apparent in due time
    through failures of science. It would be very much out of place to
    denounce such failures now, since they have not occurred. Having not yet
    understood all of biology is not a failure after just 200 years, given the
    amount of understanding already achieved. Let us speak about it again in
    1000 years. Meanwhile, metaphysicians should spare scientists their
    metaphysics and just let the scientists do their work--or join them in doing
    it.

    [My next letter to the editor follows]

    July 19, 1999

    Dear Dr....,

    Well, I guess I should have expected it, but I have to admit I'm
    disappointed. For the record I'd like to point out that the "senior [journal]
    advisor" who reviewed my recent submission ("Obstacles to gene
    duplication . . .") didn't react to my actual arguments in the paper, but to
    associations he made. The manuscript did not argue for intelligent design,
    nor did it say that complex systems would never be explained within
    Darwinian theory. Rather, it just made the simple, obvious, and unarguable
    point that gene duplication by itself is an incomplete explanation.
    Apparently, however, my skepticism about Darwinism overshadowed all
    other points. Everything I wrote beyond the first sentence was pretty much
    ignored or dismissed without engagement. I should also point out that, on
    the one hand, my paper discussed published experiments on specific genes
    in the clotting cascade of mice, the published misinterpretation of those
    experiments, and why that shows we need more information than sequence
    similarity to explain the origin of the cascade and other systems. The senior
    advisor, on the other hand, discussed our "glorious age" of biology, the
    history of science, how the world has "an intelligence much greater than
    our intelligence," God as "a being that combines consciousness, will, and
    universal power," and so on. Yet he thinks he's being scientific and I'm
    being metaphysical. Go figure.

    I must admit I'm quite surprised by your current stance, Dr..... In our email
    correspondence you wrote that you were "painfully aware of the close-
    mindedness of the scientific community to non-orthodoxy" and that you
    would entertain a manuscript from me that was "sufficiently provocative
    and lively." That led me to believe that I could express skepticism of
    Darwinism and still have a hearing. But then in your rejection letter you
    worry about "the controversial nature of your letter to [the journal]" as if
    you weren't expecting controversy, and you choose to send the manuscript
    to be reviewed by someone who says things like "If evolutionary pathways
    were difficult to find, nature faced these difficulties and solved them" (so
    there!)--not exactly the sentiments of someone with an open mind. Well,
    perhaps you've had a change of heart. That can happen if one discovers
    that the "close-mindedness of the scientific community" has some bite to it.
    But as the senior advisor bravely writes, "Let us speak about it again in
    1000 years." Perhaps by then the readers of [the journal] will be able to
    handle skepticism.

    Sincerely,

    Michael J. Behe
    Professor of Biological Sciences

    II. A lengthy response

    Later in the summer of 1999 I submitted a lengthy "Reply to Critics" paper
    to a biology journal that publishes long articles. Included in the article was
    most everything shown on this website with the exception of the articles on
    mousetraps, "The Acid Test," and sections III and following of the article
    on blood clotting. Here follows the correspondence, starting with the
    response I received, my reply, a second letter from the journal, and my final
    reply.

    [The response of the editor follows]

    23 July 1999

    Dear Dr. Behe:

    Thank you for submitting your manuscript, "Reply to My Critics," to [this
    journal]. Although the manuscript is interesting, it is our firm policy not to
    publish articles that are primarily rebuttals to criticism. Thus we cannot
    publish your article in its present form.

    Although I have no idea whether the proposal I am about to make would
    receive the endorsement of the other editors, there would be no point in
    even presenting it to them without your concurrence. The notion of
    intelligent design is one that may warrant further exploration, even though
    the topic has been dealt with extensively by both practicing scientists and
    philosophers of science. Should this exploration take the form of
    contrasting viewpoints in articles by two persons, published in the same
    issue, on the more general aspects of the topic, then our editorial policy of
    presenting current issues of significance in the biological sciences might be
    satisfied.

    Recast in more general terms, your article could present the "pro" side of
    the issue, and in that context it could address some of the criticisms that
    have appeared since your book was published, but it would have to provide
    a much broader perspective. In particular, it would have to assume a
    readership that is not familiar with your book, at least not in any detailed
    way. An accompanying article could present the "con" side of the issue,
    again taking a general perspective. No doubt your book would figure
    prominently in both articles, but the theme would be modern concepts of
    intelligent design rather than a specific publication.

    This approach would almost certainly reach a broader readership than a
    detailed response to specific criticisms. It also has the added advantage of
    allowing you to present a synopsis of your entire case rather than just
    defending specific aspects of it. Such a paired set of articles would imply
    that the topic is important, and therefore would attract additional readers.

    Let me know whether this proposal is agreeable to you. If so, we could
    discuss it at length at a future meeting of the editors (which may not be
    possible until Fall). I have no particular person in mind to present a
    contrasting viewpoint, and certainly we will not seek to identify one until
    we know what your response is to this suggestion.

    We do appreciate your interest in [this journal] as a forum for your ideas,
    and perhaps it will be possible to work out a mutually agreeable
    arrangement.

    Yours sincerely,

    [The editor]

    [My next response follows]

    August 4, 1999

    Dear Professor ...,

    Thanks very much for your letter of July 23. Yes, the proposal you outline
    would be agreeable to me--to contribute an article from a broad
    perspective discussing the "pro" side of modern concepts of intelligent
    design, to appear in the same issue as an article taking the general "con"
    side. I agree that such an arrangement would have advantages, including
    attracting the attention of a larger readership. I'd be glad to discuss
    specifics with you if the proposal receives the endorsement of the other
    editors. Please let me know when a decision is reached. Best wishes.

    Sincerely,

    Michael J. Behe
    Professor of Biological Sciences

    [The editor's next response follows]

    9 February 2000

    Dear Dr. Behe:

    We are sorry to have been delayed in getting back to you about the
    possibility of organizing a dialogue on the question of purposeful intelligent
    design. We have explored the notion with a number of individuals and have
    had extensive discussion among ourselves over a period of time.

    The editors have concluded that the journal should not undertake this
    project. The reasons are varied, but primarily they reduce to our general
    feeling that it is not possible to develop a meaningful discussion when the
    fundamental assumptions of the arguments are so different: on the one
    hand, the concept of intelligent design beyond the laws of nature is based
    on intuitive, philosophical, or religious grounds, while on the other, the
    study and explanation of all levels of the living world, including the
    molecular level, is based on scientific fact and inference.

    As you no doubt know, our journal has supported and demonstrated a
    strong evolutionary position from the very beginning, and believes that
    evolutionary explanations of all structures and phenomena of life are
    possible and inevitable. Hence a position such as yours, which opposes this
    view on other than scientific grounds, cannot be appropriate for our pages.

    Although the editors feel that there has already been extensive response to
    your position from the academic community, we nevertheless encourage
    further informed discussion in appropriate forums. Our journal cannot
    provide that forum, but we trust that other opportunities may become
    available to you.

    Yours sincerely,

    [The editorial board]

    [And my final response is below]

    February 22, 2000

    Dear [editorial board members]:

    Thank you for your letter of February 9 informing me that you have
    decided not to organize a dialogue on the question of purposeful intelligent
    design in the pages of [your journal]. I nonetheless very much appreciate
    the time and consideration you have given the issue. I agree with you that
    "the fundamental assumptions of the arguments are so different." In fact,
    your letter itself confirms this. While you attribute the conclusion of
    intelligent design to "intuitive, philosophical, or religious grounds," I
    attribute it to the same "scientific fact and inference" you claim for
    Darwinian evolution. I suppose this is one of those issues where people
    disagree about what "science" means. Again, however, I do appreciate
    your considering the project. Best wishes.

    Sincerely,

    Michael J. Behe
    Professor of Biological Sciences

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    "Darwin's own bulldog, Huxley, as Eldredge reminds us yet again, warned
    him against his insistent gradualism, but Darwin had good reason. His
    theory was largely aimed at replacing creationism as an explanation of how
    living complexity could arise out of simplicity. Complexity cannot spring
    up in a single stroke-of chance: that would be like hitting upon the
    combination number that opens a bank vault. But a whole series of tiny
    chance steps, if non-randomly selected, can build up almost limitless
    complexity of adaptation. It is as though the vault's door were to open
    another chink every time the number on the dials moved a little closer to
    the winning number. Gradualness is of the essence. In the context of the
    fight against creationism, gradualism is more or less synonymous with
    evolution itself. If you throw out gradualness you throw out the very thing
    that makes evolution more plausible than creation. Creation is a special
    case of saltation-the saltus is the large jump from nothing to fully formed
    modern life. When you think of what Darwin was fighting against, is it any
    wonder that he continually returned to the theme of slow, gradual, step-by-
    step change?" (Dawkins R., "What was all the fuss about?" Review of
    Eldredge N., "Time Frames: The Rethinking of Darwinian Evolution and
    the Theory of Punctuated Equilibria," Simon & Schuster, 1985, in Nature,
    Vol. 316, August 1985, pp.683-684).
    Stephen E. Jones | sejones@iinet.net.au | http://www.iinet.net.au/~sejones
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