Re: Information: Brad's reply (was Information: a very

Greg Billock (billgr@cco.caltech.edu)
Wed, 1 Jul 1998 17:06:08 -0700 (PDT)

Glenn,

> I am delighted that we are on the same page again. Sorry I was so slow to
> keep up with you. I have only a few comments and that concerns the
> evolution of organisms and some computer programs I have on my web page
> which attempt to mimic (at a low dimensional level) what must happen in
> sequence space.

I looked at the program...neat! I'll have to download it and play with
it.

The 'genome phase space' you mention on the page and liken to a sponge
(to produce a certain form) is a lot like we've discussed here with
relatively little of the space being "live" (producing a certain generic
form), but it being pretty distributed.

> You left out anti-evolutionists wish to find functional space be isolated
> voids (or vugs as we would say in geology about holes in limestones.) In
> that fashion there is no way to connect one functional area from another
> and it would require either megamutation or divine intervention. But given
> the functional map of cytochrome c and other proteins, one clearly has
> evidence that the functional map overlaying sequence space is quite
> connected like the holes in a sponge.

You're right, I did forget that. (And probably other interest groups :-))

-Greg