Re: human molecules in ancient hominids

John Misasi (jmisasi@engc.bu.edu)
Fri, 10 Jan 1997 17:49:48 -0500 (EST)

Glenn wrote:
>
> If human molecules are found by independent researchers in fossils whcih must
> have come from a time when no modern humans were alive, what does this say
> about their humanity. This question is primarily directed to those who do not
> believe in evolution.
>

Not saying I am anti or pro evolution, i would have the following replies:

1) I would be interested infinding out exactly how they came to the
conclusion that these were 'human molecules'. albumin is a very common
protein and i imagine if one used an antibody toward human albumin, you
could pick out albumin of many species of animal. One of the most common
albumins used expeimentally is Bovin Serum albumin (BSA), and i would bet
that anti-BSA could pick out human albumin. Also, BSA is known to stick
to just about anything.

2) If they sequenced the protein, what % is it similar to the human
albumin. Proteins with common function tend to have common sequences and
structure and therefore may be bound by an antibody to a protein from
another species.

3) I want to see data that says more than detected human protein being
present. I could probably detect human protein in lots of mammals,
especially primates, which i would assume a homonid is a member. In fact
it is a close member.

4) i read the article and it is about whether or not this age is correct
for the homonids, if it is really homonid bones, and if this finding
shows that homonids were in Euprope earlier than thought.

5) to answer your question is a cheap philosophical trick... I don't mean
to be rude, but it is. Your question leaves no room for the other person
to say anything about the homonids humanity. You are baiting a YEC in
the same way my philosophy teacher used to bait our class into answering
his questions, which no matter what he would be able to prove us wrong.
Yes, he used logic, but anyone who asks a question can always word it so
that they can respond against the other persons answer. Back to the
your question though:

How can one define
humanity? DNA, protein, spirit, soul, intelligence. If it is DNA or
protein, how much DNA or protein must be similar to be concidered human?
50%, 75%, 99%... the fact is homo sapien is greater than 99% chimpanzee.
I could ask the same question and if that is the case i can ask the same
question, what does that say about the monkey's humanity? If it is
Intellegence, we all know about intelligent animals and therefore
intellegence does not define our humanity.

What then do we have to define humanity, that is something that separates
us from the rest of the natural world? To answer this we must go to
religous perspective and this being a Christian discussion, we must look
to the Bible to see how God separates man from the other creatures:
1) God breathes life into man, giving man a spirit/soul
2) God puts man in charge of the earth
3) He cares for mankind above all other creature
4) Add your ideas here
....

the list could go on....humanity is defined by God's special actions
towards man, whether you are a YEC or an believer in evolution, God must
bless man and seperate him from the other creatures.

John Misasi

PS> BTW here is the comparison of Bovine serum albumin protein with that
from modern human using sequence data from GENBANK and the GCG software
package:

GAP of: hsa check: 6922 from: 1 to: 604


to: bsa.pep check: 561 from: 1 to: 595

TRANSLATE of: bsa check: 5229 from: 33 to: 1818
generated symbols 1 to: 595.

Symbol comparison table: /GCG/gcg/gcgcore/data/rundata/nwsgappep.cmp
CompCheck: 1254

Gap Weight: 3.000 Average Match: 0.540
Length Weight: 0.100 Average Mismatch: -0.396

Quality: 750.1 Length: 604
Ratio: 1.261 Gaps: 1
Percent Similarity: 85.882 Percent Identity: 76.807

hsa x bsa.pep January 10, 1997 17:42 ..

. . . . .
1 MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA 50
||||||||||:||||||||||||||.||||:||||||||||:||:|||||
1 MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIA 50
. . . . .
51 FAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCT 100
|.||||||||::|||||||:|||||||||||| ..|:|||||||||.||.
51 FSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCK 100
. . . . .
101 VATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLVRPEVDVMCTA 150
||.||||||:|||||.||||||||||| ||||.|:||:| :|:.:.:|..
101 VASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKL.KPDPNTLCDE 149
. . . . .
151 FHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAA 200
|..:|..|: |||||||||||||||||||::|.:|.:.| |||||.||:|
150 FKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGA 199
. . . . .
201 CLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKA 250
|||||::.:|:.. .|||:|||:|||:|||||||:|||.||||||:||||
200 CLLPKIETMREKVLTSSARQRLRCASIQKFGERALKAWSVARLSQKFPKA 249
. . . . .
251 EFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICENQDSISSKLK 300
||.||.||||||||||.||||||||||||||||||||||:|||.||||||
250 EFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLK 299
. . . . .
301 ECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVF 350
|||:||||||||||||||.|.:|.:||.|.|||.|.|||||||.||||.|
300 ECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAF 349
. . . . .
351 LGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDE 400
|| |||||.||||:|.| :||||||.||.|||.||| .|||.||..|||.
350 LGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDK 399
. . . . .
401 FKPLVEEPQNLIKQNCELFEQLGEYKFQNALLVRYTKKVPQVSTPTLVEV 450
:|.||:||||||||||: ||.|||| |||||:||||:|||||||||||||
400 LKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEV 449
. . . . .
451 SRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEKTPVSDRVTKC 500
||.|||||.:||..||..||||.|||||::||.|||||||||||::||||
450 SRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKC 499
. . . . .
501 CTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQ 550
|||||||||||||||..|||||||.|:.. ||||||||||.:.|:|||||
500 CTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQ 549
. . . . .
551 TALVELVKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEPTMRI 600
||||||:|||||||.||||.||::|.|||:||| |||||.||| |.
550 TALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEG.... 595
.
.
.